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KMID : 1011420160210040351
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Journal of Korean Ophthalmic Optics Society
2016 Volume.21 No. 4 p.351 ~ p.360
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The Effect of Difference in Main Components of Artifical Tears on Tear Film Stability of Soft Contact Lenses Wearers
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Shin Hye-Min
Park Mi-Jung
Kim So-Ra
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Abstract
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Purpose: This study aimed to investigate the effect of difference in main components of artificial tears on the tear film stability of soft contact lenses wearers.
Methods: Ninety-four eyes, age groups between twenties and thirties, with no ophthalmic disease or surgical history, were divided into two groups. According to their tear volumes, those with normal and dry eyes were asked to wear soft contact lenses made of either etafilcon A or etafilcon A with PVP for 6 hours. After instilling artificial tears containing either carboxymethyl cellulose sodium(CMC) or polysorbate 80(PS80), the stability of tear film was evaluated by measuring the non-invasive breakup time(NIBUT) and blinking rate.
Results: When wearing etafilcon A lenses in normal eyes, the increment of NIBUT with artificial tears containing CMC was greater than that of those containing PS80, both in the cases of immediately after the instillation, and 5 minutes after instillation. On the other hand, the NIBUT increase in dry eyes with etafilcon A lenses with CMC was greater than with PS80, but NIBUT increase, both with CMC and with PS80, was the same after 5 minutues. When wearing etafilcon A with PVP lenses, the NIBUT increase with artificial tears in normal eyes was not correspondingly different with the main component of artificial tears. For dry eyes, a statistically significant increase in NIBUT was found in the case of CMC than in PS80, immediately after instillation with artificial tears. However, artificial tears containing PS80 showed the continuation in NIBUT increase after 5 minutes of instillation. Regardless of the type of worn lenses, blinking rates in normal eyes after instillation of artificial tears tended to decrease after 2 minutes in the case of CMC, and in the case of PS80, their blinking rates tended to be slightly increased after instillation. On the other hand, the blinking rates of dry eyes returned to the level at pre-instillation after 2 minutes of instillation both in the cases of using CMC and PS80 instillations.
Conclusion: This study revealed that the wearers’ NIBUT and blinking rates were affected differently by instillation of artificial tears when wearing etafilcon A lens, which is due to the wearers’ tear volume and the inclusion of wetting agent when wearing etafilcon A lens. Therefore, it could be concluded that consideration of wearers’ tear volume and composition of artificial tears would be helpful to reduce discomfort due to tear film instability, especially for the case of using artificial tears with soft contact lenses.
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KEYWORD
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Artificial tear, Viscosity thickener, Surfactant, Soft contact lenses, Tear volume, Tear film stability
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